Should I be using Acquire Lite Player on PC that is part of a network domain?
No. You should ensure the PC you are using as an Acquire Lite Player is not part of a network domain. This is because a domain PC is often restricted and controlled by Group and User Policies at the Domain level.
This often results in the Outbound Ports (7200-7210), which Acquire needs to function, being blocked amongst other restrictions being controlled by the network.